Products

Immunoassay for the in vitro quantitative determination of D-Dimer concentration in human serum and plasma. Exclude pulmonary embolism in as little as 15 minutes in a near-patient setting.

D-dimer is a fibrin polymer of D-D fragments of cross-linked fibrin molecules formed under enzymolysis of plasmin. A dynamic balance between plasmin and inhibitory enzyme is maintained in able-bodied persons so that the blood circulation can be carried out normally. The fibrinolytic system in human body plays an important role in maintaining the normal permeability of blood vessel wall and the flow state of blood as well as tissue repair. To maintain normal physiological state, in the case of trauma or vascular damage , thrombus formation can prevent blood loss from damaged blood vessels. Under pathological conditions, when coagulation occurs in the body, thrombin acts on fibrin, and the fibrinolytic system is activated to degrade fibrin and form various fragments . R chain can connect two fragments containing D fragment to form D-dimer. The rise of D-dimer level represents the formation of blood clots in the vascular circulatory system. It is a sensitive marker of acute thrombosis, but it is not specific.